The influence of site conditions on structural seismic damage has become a well-known fact. How to conduct quantitative analysis of site seismic response has become one of the urgent problems to be solved in seismic engineering. This paper gives a summary of the research status of the site conditions and the influence of ground motion input on the site seismic response and the analysis methods of the site seismic response. It is shown that site conditions and ground motion input have a significant impact on analytical results of site seismic response. However，there are still some problems：The effects of the frozen soil layer are not fully considered when the site seismic response analysis is carried out in the frozen soil areas；there is no reasonable ground motion model to describe the actual ground motion accurately；the influence law of incident angle of seismic wave on seismic response of site has not been clarified；the widely used equivalent linearization method cannot fully reflect the real motion state of soil mass under the action of ground motion，so its calculation results are not reasonable. Combined with the above problems，the further research contents are prospected，which provide reference for the future research of site seismic response analysis.